Molecular characterization of resistance to macrolides in Bartonella henselae

Published Date
Journal
Antimicrobial Agents and Chemotherapy
Citation
Antimicrob Agents Chemother. 2006 Sep;50(9):3192-3
DOI
10.1128/AAC.00263-06
Authors
Biswas S
Raoult D
Rolain JM
Abstract

We selected in vitro erythromycin-resistant strains of Bartonella henselae. The mutants obtained had point mutations in domain V of 23S rRNA and/or in ribosomal protein L4. One lymph node of a patient with cat-scratch disease had such a mutation in 23S rRNA, suggesting that natural resistant strains may infect humans.